Before founding the MRC in 1987, Bozell ran the National Conservative Foundation project at the Conservative Political Action Conference, in which he moderated debates between Sam Donaldson and Bob Novak over media bias.
In 1998, Bozell founded the Conservative Communications Center. The MRC also established CNSNews.com, the site of the Conservative News Service later becoming known as Cybercast News Service, as well as numerous other MRC-affiliated web sites. On its website, MRC publishes Bozell's syndicated columns, the CyberAlert daily newsletter documenting perceived media bias, and research reports on the news media.
On his MSNBC news program Countdown with Keith Olbermann, Olbermann named Bozell the "Worst Person in the World" several times in 2006 and 2007. In response, Bozell posted a press release on the MRC site claiming that Countdown "Preaches Hate Speech". In October 2006, Bozell founded the Culture and Media Institute, an MRC branch whose mission is to reduce what he claims to be a negative liberal influence on American morality, culture, and religious liberty.