Unless there is some sort of unspoken seismic shift in offensive philosophy thats gone on, the backups you mention will primarily play with the other 2s when the game is getting out of hand. Greatwood rotates guys in some to keep everyone fresh, but they run the same stuff regardless of who is blocking and who is lined up in the backfield. For instance, DAT ran inside with great success quite a bit throughout his Duck career. Similarly, I expect them to run Freeman off tackle on the outside just like Jonathan & LeGarrett did. Tyrell & Haniteli are big strong young OLineman, but they're not bigger then Kyle Long or Mark Asper who preceded them in this offense.
I've seen no indication that they won't continue to spread teams out & read the D, taking what is there rather then forcing the issue running a Stanford/Bama smash mouth style of Offense where the cards are played face up & it's run down the opponent's throat regardless. If the opponent sells out to stop the RBs (like Texas did), Marcus will pull it and run the counter or pass it into the flats the opposite direction of the initial flow of the play. Thats how they do it
STOMP