https://en.wikipedia.org/wiki/Hallucinogen_persisting_perception_disorder
Hallucinogen persisting perception disorder (
HPPD) is a disorder characterized by a continual presence of sensory disturbances, most commonly
visual, that are reminiscent of those generated by the
use of
hallucinogenic substances. Previous use of hallucinogens by the person is
necessary, but not sufficient, for diagnosis of HPPD. For an individual to be diagnosed with HPPD, the symptoms cannot be due to another medical condition. HPPD is distinct from
flashbacks by reason of its relative permanence; while flashbacks are transient, HPPD is persistent. HPPD is a
DSM-IV diagnosis with
diagnostic code 292.89.
...
In some cases, HPPD appears to have a sudden onset after a single drug experience, strongly suggesting the drug played a direct role in triggering symptoms. But in other cases, people report gradual worsening of symptoms with ongoing drug use.[
citation needed] Drugs that have been associated with HPPD include
LSD,
[5][8]DMT,
2C-E,
2C-I,
5-MeO-DMT,
[9]MDA,
MDMA,
[10][11]psilocybin,
[12][5]diphenhydramine,
PCP,
synthetic cannabis,
zolpidem,
eszopiclone, and high doses of
dextromethorphan.[
citation needed] Additionally there are anecdotal reports of the atypical psychedelic
Salvia divinorum causing persisting symptoms consistent with HPPD.
