You may not mean it thusly, but it's really insulting to call Griner a man playing among women. She is a superstar college woman playing against other college women. She'll be a superstar pro playing among very good pros. It's like, if you're really really good, you have to be "a man".
Although she is 6'8", if you look at her, she's strong but quite slender. Look at the men of that height in the NBA and they are much broader through the shoulders and much heavier overall. So she'd have trouble in a game situation not getting pushed around. That is not to say she is an inferior player; but in basketball size and weight does count. A slender light man who was very tall would have trouble as well (think Shawn Bradley). I think a woman could compete in baseball, for example, where short and slender players have done extremely well - think 5'9" Rickey Henderson.
In a game of HORSE, I think the women could compete with the men. A shooting competition without someone who outweighs by 50 lb shoving them.
I will bet she'll have a better pro career than Felton. Or, sadly, Oden. But she still has another year of college eligibility and plans to return for her senior season.
You could say, without any argument, that the women are better educated; nearly all complete 4 years. A rarity among men.