...not really...George and Eric were good friends. But Clapton always had a crush on Harrison's wife Patti Boyd, for whom Harrison honored with the song "Something". Clapton, who was secretly and insanely in love with his friend's wife and had made several unsuccessful attempts to lure her away from George but Patti politely refused.
...So Clapton also wrote a song about her but because she was still married to George he could not use her real name for obvious reasons...so the song about his unrequited love for this woman was called "Layla".
...Patti left George a few years later and Eric finally got what we has wanted for so long...and wrote another notable song about Patti called "Wonderful Tonight".
...one woman...immortalized by 3 hit songs...don't think that's ever happened before.