That one is the be-all, end-all of bad words, though. I'm offended by very little language-wise, but that one offends me unless I hear it from a Brit, where the accent and cultural definition difference make it almost but not quite okay.
That word in Spanish--coño--is one of the mildest exclamations there are. It's like saying "damn". It's quite jarring when you hear it at first. In contrast, the word for bitch in Spanish--puta--is one of the worst things you can say. Trust me, I learned that one the hard way; "hijo de puta" is NOT COOL.