Bollinger opened the debate addressing critics, stating that "To those who believe that this event should never have happened, that it is inappropriate for the university to conduct such an event, I want to say that I understand your perspective and respect it as reasonable...it is an experiment, as all life is an experiment. This is the right thing to do and indeed, it is required by the existing norms of free speech"
Bollinger then gave his opening address, turning to Ahmadinejad and stating: "Mr. President, you exhibit all the signs of a petty and cruel dictator, and so I ask you, why have women, members of the Bahá'í Faith, homosexuals and so many of our academic colleagues become targets of persecution in your country?"
"Why do you support well-documented terrorist organizations that continue to strike at peace and democracy in the Middle East, destroying lives and the civil society of the region? Frankly, and in all candor Mr. President, I doubt that you will have the intellectual courage to answer these questions, but your avoiding them will in itself be meaningful to us. I do expect you to exhibit the fanatical mind-set that characterizes what you say and do."