OT Coronavirus: America in chaos, News and Updates. One million Americans dead and counting (3 Viewers)

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Just got back from getting gas for mower all the stores are packed out, and roads just as busy as normal.
Joggers and walkers everywhere, which is cool and admirable! Maybe 50% have mask on.
Went to the doc this am and had to put mask on and they took my temp.
 
A mutant coronavirus has emerged, even more contagious than the original, study says

Scientists have identified a new strain of the coronavirus that has become dominant worldwide and appears to be more contagious than the versions that spread in the early days of the COVID-19 pandemic, according to a new study led by scientists at Los Alamos National Laboratory.

The new strain appeared in February in Europe, migrated quickly to the East Coast of the United States and has been the dominant strain across the world since mid-March, the scientists wrote.

In addition to spreading faster, it may make people vulnerable to a second infection after a first bout with the disease, the report warned.

The 33-page report was posted Thursday on BioRxiv, a website that researchers use to share their work before it is peer reviewed, an effort to speed up collaborations with scientists working on COVID-19 vaccines or treatments. That research has been largely based on the genetic sequence of earlier strains and might not be effective against the new one.

The mutation identified in the new report affects the now infamous spikes on the exterior of the coronavirus, which allow it to enter human respiratory cells. The report’s authors said they felt an “urgent need for an early warning” so that vaccines and drugs under development around the world will be effective against the mutated strain.

Wherever the new strain appeared, it quickly infected far more people than the earlier strains that came out of Wuhan, China, and within weeks it was the only strain that was prevalent in some nations, according to the report. The new strain’s dominance over its predecessors demonstrates that it is more infectious, according to the report, though exactly why is not yet known.

The coronavirus, known to scientists as SARS-CoV-2, has infected more than 3.5 million people around the world and caused more than 250,000 COVID-19 deaths since its discovery late last year.

The report was based on a computational analysis of more than 6,000 coronavirus sequences from around the world, collected by the Global Initiative for Sharing All Influenza Data, a public-private organization in Germany. Time and again, the analysis found the new version was transitioning to become dominant.

The Los Alamos team, assisted by scientists at Duke University and the University of Sheffield in England, identified 14 mutations. Those mutations occurred among the nearly 30,000 base pairs of RNA that other scientists say make up the coronavirus’s genome. The report authors focused on a mutation called D614G, which is responsible for the change in the virus’ spikes.

“The story is worrying, as we see a mutated form of the virus very rapidly emerging, and over the month of March becoming the dominant pandemic form,” study leader Bette Korber, a computational biologist at Los Alamos, wrote on her Facebook page. “When viruses with this mutation enter a population, they rapidly begin to take over the local epidemic, thus they are more transmissible.”

While the Los Alamos report is highly technical and dispassionate, Korber expressed some deep personal feelings about the implications of the finding in her Facebook post.

“This is hard news,” wrote Korber, “but please don’t only be disheartened by it. Our team at LANL was able to document this mutation and its impact on transmission only because of a massive global effort of clinical people and experimental groups, who make new sequences of the virus (SARS-CoV-2) in their local communities available as quickly as they possibly can.”

Korber, a graduate of Cal State Long Beach who went on to earn a PhD in chemistry at Caltech, joined the lab in 1990 and focused much of her work on an HIV vaccine. In 2004, she won the Ernest Orlando Lawrence Award, the U.S. Department of Energy’s highest recognition for scientific achievement. She contributed a portion of the financial prize to help establish an orphanage for young AIDS victims in South Africa.

The report contains regional breakdowns of when the new strain of virus first emerged and how long it took to become dominant.

Italy was one of the first countries to see the new virus in the last week of February, almost at the same time that the original strain appeared. Washington was among the first states to get hit with the original strain in late February, but by March 15 the mutated strain dominated. New York was hit by the original virus around March 15, but within days the mutant strain took over. The team did not report results for California.

Scientists at major organizations working on a vaccine or drugs have told The Times that they are pinning their hopes on initial evidence that the virus is stable and not likely to mutate the way influenza virus does, requiring a new vaccine every year. The Los Alamos report could upend that assumption.

If the pandemic fails to wane seasonally as the weather warms, the study warns, the virus could undergo further mutations even as research organizations prepare the first medical treatments and vaccines. Without getting on top of the risk now, the effectiveness of vaccines could be limited. Some of the compounds in development are supposed to latch onto the spike or interrupt its action. If they were designed based on the original version of the spike, they might not be effective against the new coronavirus strain, the study’s authors warned.

“We cannot afford to be blindsided as we move vaccines and antibodies into clinical testing,” Korber wrote on Facebook. “Please be encouraged by knowing the global scientific community is on this, and we are cooperating with each other in ways I have never seen … in my 30 years as a scientist.”

David Montefiori, a Duke University scientist who worked on the report said it is the first to document a mutation in the coronavirus that appears to make it more infectious.

Although the researchers don’t yet know the details about how the mutated spike behaves inside the body, it’s clearly doing something that gives it an evolutionary advantage over its predecessor and is fueling its rapid spread. One scientist called it a “classic case of Darwinian evolution.”

“D614G is increasing in frequency at an alarming rate, indicating a fitness advantage relative to the original Wuhan strain that enables more rapid spread,” the study said.

Still unknown is whether this mutant virus could account for regional variations in how hard COVID-19 is hitting different parts of the world.

In the United States, doctors had begun to independently question whether new strains of the virus could account for the differences in how it has infected, sickened and killed people, said Alan Wu, a UC San Francisco professor who runs the clinical chemistry and toxicology laboratories at San Francisco General Hospital.

Medical experts have speculated in recent weeks that they were seeing at least two strains of the virus in the U.S., one prevalent on the East Coast and another on the West Coast, according to Wu.

“We are looking to identify the mutation,” he said, noting that his hospital has had only a few deaths out of the hundreds of cases it has treated, which is “quite a different story than we are hearing from New York.”

The Los Alamos study does not indicate that the new version of the virus is more lethal than the original. People infected with the mutated strain appear to have higher viral loads. But the study’s authors from the University of Sheffield found that among a local sample of 447 patients, hospitalization rates were about the same for people infected with either virus version.

Even if the new strain is no more dangerous than the others, it could still complicate efforts to bring the pandemic under control. That would be an issueif the mutation makes the virus so different from earlier strains that people who have immunity to them would not be immune to the new version.

If that is indeed the case, it could make “individuals susceptible to a second infection,” the study authors wrote.

It’s possible that the mutation changes the spike in some way that helps the virus evade the immune system, said Montefiori, who has worked on an HIV vaccine for 30 years. “It is hypothetical. We are looking at it very hard.”

———

©2020 Los Angeles Times

 
BigGameDamian said:
https://www.google.com/amp/s/www.latimes.com/california/story/2020-05-05/mutant-coronavirus-has-emerged-more-contagious-than-original?_amp=true

Scientists say a now-dominant strain of the coronavirus appears to be more contagious than original
Click to expand...

SlyPokerDog said:
A mutant coronavirus has emerged, even more contagious than the original, study says

Scientists have identified a new strain of the coronavirus that has become dominant worldwide and appears to be more contagious than the versions that spread in the early days of the COVID-19 pandemic, according to a new study led by scientists at Los Alamos National Laboratory.

The new strain appeared in February in Europe, migrated quickly to the East Coast of the United States and has been the dominant strain across the world since mid-March, the scientists wrote.

In addition to spreading faster, it may make people vulnerable to a second infection after a first bout with the disease, the report warned.

The 33-page report was posted Thursday on BioRxiv, a website that researchers use to share their work before it is peer reviewed, an effort to speed up collaborations with scientists working on COVID-19 vaccines or treatments. That research has been largely based on the genetic sequence of earlier strains and might not be effective against the new one.

The mutation identified in the new report affects the now infamous spikes on the exterior of the coronavirus, which allow it to enter human respiratory cells. The report’s authors said they felt an “urgent need for an early warning” so that vaccines and drugs under development around the world will be effective against the mutated strain.

Wherever the new strain appeared, it quickly infected far more people than the earlier strains that came out of Wuhan, China, and within weeks it was the only strain that was prevalent in some nations, according to the report. The new strain’s dominance over its predecessors demonstrates that it is more infectious, according to the report, though exactly why is not yet known.

The coronavirus, known to scientists as SARS-CoV-2, has infected more than 3.5 million people around the world and caused more than 250,000 COVID-19 deaths since its discovery late last year.

The report was based on a computational analysis of more than 6,000 coronavirus sequences from around the world, collected by the Global Initiative for Sharing All Influenza Data, a public-private organization in Germany. Time and again, the analysis found the new version was transitioning to become dominant.

The Los Alamos team, assisted by scientists at Duke University and the University of Sheffield in England, identified 14 mutations. Those mutations occurred among the nearly 30,000 base pairs of RNA that other scientists say make up the coronavirus’s genome. The report authors focused on a mutation called D614G, which is responsible for the change in the virus’ spikes.

“The story is worrying, as we see a mutated form of the virus very rapidly emerging, and over the month of March becoming the dominant pandemic form,” study leader Bette Korber, a computational biologist at Los Alamos, wrote on her Facebook page. “When viruses with this mutation enter a population, they rapidly begin to take over the local epidemic, thus they are more transmissible.”

While the Los Alamos report is highly technical and dispassionate, Korber expressed some deep personal feelings about the implications of the finding in her Facebook post.

“This is hard news,” wrote Korber, “but please don’t only be disheartened by it. Our team at LANL was able to document this mutation and its impact on transmission only because of a massive global effort of clinical people and experimental groups, who make new sequences of the virus (SARS-CoV-2) in their local communities available as quickly as they possibly can.”

Korber, a graduate of Cal State Long Beach who went on to earn a PhD in chemistry at Caltech, joined the lab in 1990 and focused much of her work on an HIV vaccine. In 2004, she won the Ernest Orlando Lawrence Award, the U.S. Department of Energy’s highest recognition for scientific achievement. She contributed a portion of the financial prize to help establish an orphanage for young AIDS victims in South Africa.

The report contains regional breakdowns of when the new strain of virus first emerged and how long it took to become dominant.

Italy was one of the first countries to see the new virus in the last week of February, almost at the same time that the original strain appeared. Washington was among the first states to get hit with the original strain in late February, but by March 15 the mutated strain dominated. New York was hit by the original virus around March 15, but within days the mutant strain took over. The team did not report results for California.

Scientists at major organizations working on a vaccine or drugs have told The Times that they are pinning their hopes on initial evidence that the virus is stable and not likely to mutate the way influenza virus does, requiring a new vaccine every year. The Los Alamos report could upend that assumption.

If the pandemic fails to wane seasonally as the weather warms, the study warns, the virus could undergo further mutations even as research organizations prepare the first medical treatments and vaccines. Without getting on top of the risk now, the effectiveness of vaccines could be limited. Some of the compounds in development are supposed to latch onto the spike or interrupt its action. If they were designed based on the original version of the spike, they might not be effective against the new coronavirus strain, the study’s authors warned.

“We cannot afford to be blindsided as we move vaccines and antibodies into clinical testing,” Korber wrote on Facebook. “Please be encouraged by knowing the global scientific community is on this, and we are cooperating with each other in ways I have never seen … in my 30 years as a scientist.”

David Montefiori, a Duke University scientist who worked on the report said it is the first to document a mutation in the coronavirus that appears to make it more infectious.

Although the researchers don’t yet know the details about how the mutated spike behaves inside the body, it’s clearly doing something that gives it an evolutionary advantage over its predecessor and is fueling its rapid spread. One scientist called it a “classic case of Darwinian evolution.”

“D614G is increasing in frequency at an alarming rate, indicating a fitness advantage relative to the original Wuhan strain that enables more rapid spread,” the study said.

Still unknown is whether this mutant virus could account for regional variations in how hard COVID-19 is hitting different parts of the world.

In the United States, doctors had begun to independently question whether new strains of the virus could account for the differences in how it has infected, sickened and killed people, said Alan Wu, a UC San Francisco professor who runs the clinical chemistry and toxicology laboratories at San Francisco General Hospital.

Medical experts have speculated in recent weeks that they were seeing at least two strains of the virus in the U.S., one prevalent on the East Coast and another on the West Coast, according to Wu.

“We are looking to identify the mutation,” he said, noting that his hospital has had only a few deaths out of the hundreds of cases it has treated, which is “quite a different story than we are hearing from New York.”

The Los Alamos study does not indicate that the new version of the virus is more lethal than the original. People infected with the mutated strain appear to have higher viral loads. But the study’s authors from the University of Sheffield found that among a local sample of 447 patients, hospitalization rates were about the same for people infected with either virus version.

Even if the new strain is no more dangerous than the others, it could still complicate efforts to bring the pandemic under control. That would be an issueif the mutation makes the virus so different from earlier strains that people who have immunity to them would not be immune to the new version.

If that is indeed the case, it could make “individuals susceptible to a second infection,” the study authors wrote.

It’s possible that the mutation changes the spike in some way that helps the virus evade the immune system, said Montefiori, who has worked on an HIV vaccine for 30 years. “It is hypothetical. We are looking at it very hard.”

———

©2020 Los Angeles Times
Click to expand...


Aww, fuck it ...let's go ahead and open up the country anyway.
 
SlyPokerDog said:
A mutant coronavirus has emerged, even more contagious than the original, study says

Scientists have identified a new strain of the coronavirus that has become dominant worldwide and appears to be more contagious than the versions that spread in the early days of the COVID-19 pandemic, according to a new study led by scientists at Los Alamos National Laboratory.

The new strain appeared in February in Europe, migrated quickly to the East Coast of the United States and has been the dominant strain across the world since mid-March, the scientists wrote.

In addition to spreading faster, it may make people vulnerable to a second infection after a first bout with the disease, the report warned.

The 33-page report was posted Thursday on BioRxiv, a website that researchers use to share their work before it is peer reviewed, an effort to speed up collaborations with scientists working on COVID-19 vaccines or treatments. That research has been largely based on the genetic sequence of earlier strains and might not be effective against the new one.

The mutation identified in the new report affects the now infamous spikes on the exterior of the coronavirus, which allow it to enter human respiratory cells. The report’s authors said they felt an “urgent need for an early warning” so that vaccines and drugs under development around the world will be effective against the mutated strain.

Wherever the new strain appeared, it quickly infected far more people than the earlier strains that came out of Wuhan, China, and within weeks it was the only strain that was prevalent in some nations, according to the report. The new strain’s dominance over its predecessors demonstrates that it is more infectious, according to the report, though exactly why is not yet known.

The coronavirus, known to scientists as SARS-CoV-2, has infected more than 3.5 million people around the world and caused more than 250,000 COVID-19 deaths since its discovery late last year.

The report was based on a computational analysis of more than 6,000 coronavirus sequences from around the world, collected by the Global Initiative for Sharing All Influenza Data, a public-private organization in Germany. Time and again, the analysis found the new version was transitioning to become dominant.

The Los Alamos team, assisted by scientists at Duke University and the University of Sheffield in England, identified 14 mutations. Those mutations occurred among the nearly 30,000 base pairs of RNA that other scientists say make up the coronavirus’s genome. The report authors focused on a mutation called D614G, which is responsible for the change in the virus’ spikes.

“The story is worrying, as we see a mutated form of the virus very rapidly emerging, and over the month of March becoming the dominant pandemic form,” study leader Bette Korber, a computational biologist at Los Alamos, wrote on her Facebook page. “When viruses with this mutation enter a population, they rapidly begin to take over the local epidemic, thus they are more transmissible.”

While the Los Alamos report is highly technical and dispassionate, Korber expressed some deep personal feelings about the implications of the finding in her Facebook post.

“This is hard news,” wrote Korber, “but please don’t only be disheartened by it. Our team at LANL was able to document this mutation and its impact on transmission only because of a massive global effort of clinical people and experimental groups, who make new sequences of the virus (SARS-CoV-2) in their local communities available as quickly as they possibly can.”

Korber, a graduate of Cal State Long Beach who went on to earn a PhD in chemistry at Caltech, joined the lab in 1990 and focused much of her work on an HIV vaccine. In 2004, she won the Ernest Orlando Lawrence Award, the U.S. Department of Energy’s highest recognition for scientific achievement. She contributed a portion of the financial prize to help establish an orphanage for young AIDS victims in South Africa.

The report contains regional breakdowns of when the new strain of virus first emerged and how long it took to become dominant.

Italy was one of the first countries to see the new virus in the last week of February, almost at the same time that the original strain appeared. Washington was among the first states to get hit with the original strain in late February, but by March 15 the mutated strain dominated. New York was hit by the original virus around March 15, but within days the mutant strain took over. The team did not report results for California.

Scientists at major organizations working on a vaccine or drugs have told The Times that they are pinning their hopes on initial evidence that the virus is stable and not likely to mutate the way influenza virus does, requiring a new vaccine every year. The Los Alamos report could upend that assumption.

If the pandemic fails to wane seasonally as the weather warms, the study warns, the virus could undergo further mutations even as research organizations prepare the first medical treatments and vaccines. Without getting on top of the risk now, the effectiveness of vaccines could be limited. Some of the compounds in development are supposed to latch onto the spike or interrupt its action. If they were designed based on the original version of the spike, they might not be effective against the new coronavirus strain, the study’s authors warned.

“We cannot afford to be blindsided as we move vaccines and antibodies into clinical testing,” Korber wrote on Facebook. “Please be encouraged by knowing the global scientific community is on this, and we are cooperating with each other in ways I have never seen … in my 30 years as a scientist.”

David Montefiori, a Duke University scientist who worked on the report said it is the first to document a mutation in the coronavirus that appears to make it more infectious.

Although the researchers don’t yet know the details about how the mutated spike behaves inside the body, it’s clearly doing something that gives it an evolutionary advantage over its predecessor and is fueling its rapid spread. One scientist called it a “classic case of Darwinian evolution.”

“D614G is increasing in frequency at an alarming rate, indicating a fitness advantage relative to the original Wuhan strain that enables more rapid spread,” the study said.

Still unknown is whether this mutant virus could account for regional variations in how hard COVID-19 is hitting different parts of the world.

In the United States, doctors had begun to independently question whether new strains of the virus could account for the differences in how it has infected, sickened and killed people, said Alan Wu, a UC San Francisco professor who runs the clinical chemistry and toxicology laboratories at San Francisco General Hospital.

Medical experts have speculated in recent weeks that they were seeing at least two strains of the virus in the U.S., one prevalent on the East Coast and another on the West Coast, according to Wu.

“We are looking to identify the mutation,” he said, noting that his hospital has had only a few deaths out of the hundreds of cases it has treated, which is “quite a different story than we are hearing from New York.”

The Los Alamos study does not indicate that the new version of the virus is more lethal than the original. People infected with the mutated strain appear to have higher viral loads. But the study’s authors from the University of Sheffield found that among a local sample of 447 patients, hospitalization rates were about the same for people infected with either virus version.

Even if the new strain is no more dangerous than the others, it could still complicate efforts to bring the pandemic under control. That would be an issueif the mutation makes the virus so different from earlier strains that people who have immunity to them would not be immune to the new version.

If that is indeed the case, it could make “individuals susceptible to a second infection,” the study authors wrote.

It’s possible that the mutation changes the spike in some way that helps the virus evade the immune system, said Montefiori, who has worked on an HIV vaccine for 30 years. “It is hypothetical. We are looking at it very hard.”

———

©2020 Los Angeles Times
Click to expand...
 
https://abcnews.go.com/Politics/doj...id=clicksource_4380645_4_three_posts_card_hed

DOJ announces first charges of alleged COVID-19 stimulus relief fraud
The department says two men fraudulently sought nearly half a million in loans.
ABC News
The Justice Department announced its first series of charges targeting fraud in the COVID-19 stimulus relief package for small businesses on Tuesday after two Rhode Island men allegedly filed for more than half a million dollars in loans to help pay employees that the government says do not exist.

Federal prosecutors said David Staveley and David Butziger fraudulently applied for forgivable loans from the Small Business Association's established under the Coronavirus Aid, Relief, and Economic Security (CARES) Act passed by Congress last month.

According to court documents, both claimed to have "dozens of employees" across several different businesses, but the government said in actuality they had "no salaried employees" and in one instance applied for a loan "to pay employees at a business [they] did not own."
 
magnifier661 said:
https://abcnews.go.com/Politics/doj...id=clicksource_4380645_4_three_posts_card_hed

DOJ announces first charges of alleged COVID-19 stimulus relief fraud
The department says two men fraudulently sought nearly half a million in loans.
ABC News
The Justice Department announced its first series of charges targeting fraud in the COVID-19 stimulus relief package for small businesses on Tuesday after two Rhode Island men allegedly filed for more than half a million dollars in loans to help pay employees that the government says do not exist.

Federal prosecutors said David Staveley and David Butziger fraudulently applied for forgivable loans from the Small Business Association's established under the Coronavirus Aid, Relief, and Economic Security (CARES) Act passed by Congress last month.

According to court documents, both claimed to have "dozens of employees" across several different businesses, but the government said in actuality they had "no salaried employees" and in one instance applied for a loan "to pay employees at a business [they] did not own."
Click to expand...

Oh yeah, are they going to charge the Lakers too
 
Cops arrest armed men, Texas bar owner who violated order to close

Cops in western Texas said they arrested a bar owner and a group of armed men Monday after they violated the state's order.

Ector County Sheriff Mike Griffis said during a news conference Tuesday that his officers were alerted that the owner of Big Daddy Zane's in West Odessa, Texas, opened her bar even though Gov. Greg Abbott's reopening plan explicitly mandated that bars remain closed. When officers arrived, they saw six men in body armor and armed rifles standing outside the establishment, according to Griffis.

"This was not a protest of their second amendment rights. It was a show of force to ensure this lady could violate the governor’s order," Griffis told reporters.

https://abcnews.go.com/US/cops-arrest-armed-men-texas-bar-owner-violated/story?id=70509866

odessa-arrests-3-ap-rc-200505_hpEmbed_11x8_992.jpg
 
Yo, how are we gonna get haircuts now? We gonna have to wear some kind of mask set up?
 
Shit, no haircut in 2 months. Literally no one in history has suffered as badly as we have.
 
EL PRESIDENTE said:
Shit, no haircut in 2 months. Literally no one in history has suffered as badly as we have.
Click to expand...
I invested long ago in the survival tool called, "hairclippers and scissors"....also invested in one of those new fangled electric razors....no mirror though
 
https://www.cnbc.com/amp/2020/05/05/coronavirus-nordstrom-is-preparing-to-reopen-its-stores.html

Nordstrom is preparing to reopen its stores. Here's what the retailer is changing

KEY POINTS
  • "Our stores won't open all at once," Pete and Erik Nordstrom said.
  • The precautionary steps the company is taking include: Closing some fitting rooms; adding plexiglass dividers at registers; temporarily suspending some services; and offering additional curbside pickup.
  • "As our stores reopen we will evolve the way we offer personalized service," the company said.
 
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