Yep, that is not an attractive (or most importantly, healthy) look for someone in their early 40's. That's a body that has been starved, beaten, and abused. Take away the unnecessary plastic surgery, she just looks like she hasn't eaten healthily for a long time. Obviously that can be done multiple ways (way over-eating vs way under eating, etc).
That is not a look of someone who is naturally skinny (like Calista Flockhart, she was naturally skinny). This is someone who has altered their body to the point where they're unrecognizable. Same with Lindsay Lohan.
I'm sure there are examples of men who have done this (or in some cases, jacked up their bodies to the point of being unrecognizable). Hell, look at Michael Jackson, he altered his body so much he started to look alien, and it was obvious he was unhealthy and had an assortment of issues.